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Chemical & Physical Characteristics Compound Class: Small-molecule NNMT inhibitor (quinolinium derivative) Molecular Formula: CHN Appearance: Off-white to pale yellow powder, encapsulated for oral research administration Solubility: Water-soluble

To reconcile the opposite effects of V-ATPase dysfunction on autophagy flux in nutrient-rich versus starvation medium, we reasoned that dysfunction of the V-ATPase may have dual roles in autophagy regulation: On the one hand, it hampers vacuolar hydrolytic activities (but vacuolar proteases such as Pep4 are still partially active)

AOD-9604 is supplied as a research grade synthetic peptide reference compound intended exclusively for controlled laboratory and analytical environments